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Rated 4.9 out of 5
Based on 162 reviews
162
Radical Relief Gel Roll On

25% active ingredients — 5x more than the leading topical pain products. Roll it on. Feel the cooling, then the warmth..Feel it work. No pills. No mess. No prescription.*


✓  Menthol + Methyl Salicylate — dual-action: cooling then warming

✓  Arnica Montana Oil — used by athletes for bruising and muscle soreness

✓  Cryosphere applicator — massages directly into muscle and joint tissue


★★★★★  Tested by athletes. Viral for PMS cramp relief.


Free shipping on qualifying orders over $75  |  No prescription  |  No swallowing

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$39.20

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One-time purchase

30 Day Supply

$49.00

Third-Party Tested

Ingredient identity and potency

Heavy metals (lead, mercury, arsenic, cadmium)

Microbial contamination

Why it matters: Up to 40% of supplements on the market don't contain what's on the label. We refuse to be one of them.


The Mechanism

25% Active. Why That Number Matters.

Most topical pain gels contain 5-10% active ingredients.

Radical Relief contains 25%. That's not a minor difference.

That's the difference between something you feel working and something you apply and then wonder about.

COOLING

Cooling (Menthol)

Menthol activates cold-sensitive receptors in the skin, producing an immediate cooling sensation that helps temporarily relieve minor pain. This is why you feel it working within seconds — not minutes.

The
Cryosphere
Applicator

The roll-on ball is designed to apply pressure and massage the gel directly into the target area — amplifying absorption and adding mechanical tension release simultaneously. You're not just applying a product. You're massaging and treating at once.

View Full Ingredient Panel

The Mechanism

25% Active. Why That Number Matters.

Most topical pain gels contain 5–10% active ingredients.

Radical Relief contains 25%.

That's not a minor difference. That's the difference between something you feel working and something you apply and then wonder about.

The Cryosphere Applicator

The roll-on ball is designed to apply pressure and massage the gel directly into the target area — amplifying absorption and adding mechanical tension release simultaneously. You're not just applying a product. You're massaging and treating at once.

View Full Ingredient Panel

Verified 5 Star Reviews

These are real ASYSTEM customers who have experienced the amazing benefits of Radical Relief Gel Roll On, and they want more people to know about it.

Migraine Champion

I started using the asystem radical relief gel roll on about a year ago, and I am never looking back. I suffer from chronic migraine and had always relied on a dab of peppermint oil to my temples which was a bit tingly, but not cutting it. This roller is super easy to use. I carry it with me everywhere and have one at the office, my home desk, in my purse and on my nighstand. I love using it on my temples, back of my neck, my jaw and my shoulders for migraine tension, TMJ, sinus pressure, chronic shoulder pain brought on by fibromyalgia and just any icky feeling that pops up. One of my must-have items!


Logan S.B.

How did I not know about Radical Relief?

OMG! What a game changer! I suffer from residual pain after two meniscus repairs. I just roll some Radical Relief on my knee joints; wait for it to dry and I’m off! It’s amazing. Works fast and helps me get through my day literally pain free. Buy it now! It was out of stock for months. On second thought, buy 2. Give one to a friend so they can diminish their pain, too!


Mel F.

Best roll on.. EVER!!

I suffer from chronic migraines and debilitating menstrual cramps. Not anymore thanks to this stuff!! Knowing it’s also all natural, is even better. It literally melts pain away instantly and the smell is exactly like polar ice gum by eclipse. If you’ve considered purchasing this, just do it! Your body will thank you!


— Kerra V.

Amazing for period cramps

Normally I need to take 2-3 Advils for my period cramps on my first day. I used this a couple times throughout the day and not only was the pain relieved within seconds to minutes, I did not have to take a single painkiller that day. This stuff is amazing and I will be back for more!

— Jennifer

Move over icy hot!

About 2 months back I ordered this after getting hurt on a trampoline. To this day I'm still dealing with whiplash from the accident, but this product makes the days a little bit easier. Last week I packed this in my toiletries for a work trip when I had a little pain come on. Out of laziness I saw the icy hot tube in my bathroom and thought "this will do" Man, I thought the radical relief gel roll on was great before, but after going back to icy hot one time, I realized how much I LOVE the radical relief gel roll on. The ASYSTEM scent, effect, and applicator are all a million times better. PRO TIP: Before using, turn it upside down and give it a little shake. It helps get the product onto the roller easier.


— Jacob

I'm floored

I've had consistent, unrelenting hip joint pain for a few years now. I've tried to many topicals, stretch routines, rest, etc. to no avail. About 20 mins after applying this I suddenly realized - I feel NOTHING in my hip, in the best way! Wanted to share my first-ever online review because I'm truly so happy to have found this product.

— Tori

Finally found something that works.

My husband and I have suffered from chronic back pain for many years. This is the first topical product that we can both use and feel real relief with!! We are consistent buyers and are always sad when it is out of stock and we are running low. Thank you for helping us!!

— Amanda P.

Migraine Champion

I started using the asystem radical relief gel roll on about a year ago, and I am never looking back. I suffer from chronic migraine and had always relied on a dab of peppermint oil to my temples which was a bit tingly, but not cutting it. This roller is super easy to use. I carry it with me everywhere and have one at the office, my home desk, in my purse and on my nighstand. I love using it on my temples, back of my neck, my jaw and my shoulders for migraine tension, TMJ, sinus pressure, chronic shoulder pain brought on by fibromyalgia and just any icky feeling that pops up. One of my must-have items!


Logan S.B.

How did I not know about Radical Relief?

OMG! What a game changer! I suffer from residual pain after two meniscus repairs. I just roll some Radical Relief on my knee joints; wait for it to dry and I’m off! It’s amazing. Works fast and helps me get through my day literally pain free. Buy it now! It was out of stock for months. On second thought, buy 2. Give one to a friend so they can diminish their pain, too!


Mel F.

Best roll on.. EVER!!

I suffer from chronic migraines and debilitating menstrual cramps. Not anymore thanks to this stuff!! Knowing it’s also all natural, is even better. It literally melts pain away instantly and the smell is exactly like polar ice gum by eclipse. If you’ve considered purchasing this, just do it! Your body will thank you!


— Kerra V.

Amazing for period cramps

Normally I need to take 2-3 Advils for my period cramps on my first day. I used this a couple times throughout the day and not only was the pain relieved within seconds to minutes, I did not have to take a single painkiller that day. This stuff is amazing and I will be back for more!

— Jennifer

Move over icy hot!

About 2 months back I ordered this after getting hurt on a trampoline. To this day I'm still dealing with whiplash from the accident, but this product makes the days a little bit easier. Last week I packed this in my toiletries for a work trip when I had a little pain come on. Out of laziness I saw the icy hot tube in my bathroom and thought "this will do" Man, I thought the radical relief gel roll on was great before, but after going back to icy hot one time, I realized how much I LOVE the radical relief gel roll on. The ASYSTEM scent, effect, and applicator are all a million times better. PRO TIP: Before using, turn it upside down and give it a little shake. It helps get the product onto the roller easier.


— Jacob

I'm floored

I've had consistent, unrelenting hip joint pain for a few years now. I've tried to many topicals, stretch routines, rest, etc. to no avail. About 20 mins after applying this I suddenly realized - I feel NOTHING in my hip, in the best way! Wanted to share my first-ever online review because I'm truly so happy to have found this product.

— Tori

Finally found something that works.

My husband and I have suffered from chronic back pain for many years. This is the first topical product that we can both use and feel real relief with!! We are consistent buyers and are always sad when it is out of stock and we are running low. Thank you for helping us!!

— Amanda P.

When to Use It

Post-Workout Soreness

Roll onto quads, hamstrings, calves, or back within 30 minutes of training. The cooling-to-warming sequence helps temporarily relieve muscle soreness and tension release.*

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Period Cramps

Roll directly onto the lower abdomen. The warming action supports muscle relaxation in the

smooth muscle tissue responsible for cramping.* This use went viral — it's one of our most cited

reviews.

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Neck + Shoulder Tension

Common from desk work, long commutes, or stress-related tension. Apply to the trapezius and

upper back — the cryosphere applicator helps work into tight areas.

Headaches

Roll onto the temples and base of the skull. The cooling sensation provides immediate sensory

relief from tension headache discomfort.*

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Joint Discomfort

Apply directly to the joint. The formula is designed to absorb, not just sit on the surface.*

One product. In the gym bag, the desk drawer, and the bathroom cabinet.

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When To Use It

One product. In the gym bag, the desk drawer, and the bathroom cabinet.

Radical Relief vs. Standard Topicals

Formulated with high-potency active ingredients and paired with a precision cryosphere applicator designed to support targeted massage application, Radical Relief delivers a differentiated topical experience from many traditional roll-ons and creams.

WHO USES IT

Athletes

For post-training recovery: muscle soreness, joint discomfort, and the kind of tension that limits your next session.

People With Desk Jobs

Neck, shoulder, and upper back tension from hours of static posture. The cryosphere applicator was built for this.

People who experience PMS cramps

The most viral use of Radical Relief. Roll directly onto the lower abdomen for warming muscle relief.* No pills. No waiting for absorption. Immediate sensory effect.

Anyone who wants to avoid pills

Topical application delivers relief directly to the site — without passing through the digestive system and with no systemic effects.

Travelers

TSA-compliant. Fits in a gym bag or carry-on. No refrigeration.

WHO USES IT

Athletes

For post-training recovery: muscle soreness, joint discomfort, and the kind of tension that limits your next session.

People with desk jobs

Neck, shoulder, and upper back tension from hours of static posture. The cryosphere applicator was built for this.

People with PMS cramps

The most viral use of Radical Relief. Roll directly onto the lower abdomen for warming muscle

relief.* No pills. No waiting for absorption. Immediate sensory effect.

People wanting to avoid pills

Topical application delivers relief directly to the site — without passing through the digestive

system and with no systemic effects.

Travelers

TSA-compliant. Fits in a gym bag or carry-on. No refrigeration.

Built on Transparency Not Hype

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FAQs

More questions? Email us at help@asystem.com — our real human support team is available Monday–Friday and typically responds within 24 hours.

25% Active. Cryosphere Applicator. Works Where You Apply It.

ROLL ON. FEEL IT IN SECONDS

$49.00

$39.20 every
90 days

Free shipping on qualifying orders | No mess | No pills | No waiting

*Use only as directed. See Drug Facts for full information, including warnings. For external use only. Avoid contact with eyes and broken skin. Individual results may vary.